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Avascular Necrosis The Journey
Posted on July 28 2015
Osteonecrosis has several causes. Loss of blood supply to the bone can be caused by an injury (trauma-related osteonecrosis or joint dislocation) or by certain risk factors (nontraumatic osteonecrosis), such as some medications (steroids), blood coagulation disorders,patients on Chemo,Trauma to joint, or excessive alcohol use. Increased pressure within the bone also is associated with osteonecrosis. The pressure within the bone causes the blood vessels to narrow, making it hard for the vessels to deliver enough blood to the bone cells.
When a joint is injured, as in a fracture or dislocation, the blood vessels may be damaged. This can interfere with the blood circulation to the bone and lead to trauma-related osteonecrosis
Synonyms of Osteonecrosis
Avascular Necrosis of Bone
Ischemic Necrosis of Bone
Osteonecrosis, also known as avascular necrosis, is a disease resulting from the temporary or permanent loss of the blood supply to the bones. Without blood, the bone tissue dies and causes the bone to collapse. If the process involves the bones near a joint, it often leads to collapse of the joint surface. This disease also is known, aseptic necrosis, and ischemic bone necrosis.
Although it can happen in any bone, osteonecrosis most commonly affects the ends(epiphysis) of long bones such as the femur, the bone extending from the knee joint to the hip joint. Other common sites include the upper arm bone, knees, shoulders, and ankles. The disease may affect just one bone, more than one bone at the same time, or more than one bone at different times. Orthopaedic doctors most often diagnose the disease.
The amount of disability that results from osteonecrosis depends on what part of the bone is affected, how large an area is involved, and how effectively the bone rebuilds itself. The process of bone rebuilding takes place after an injury as well as during normal growth. Normally, bone continuously breaks down and rebuilds--old bone is reabsorbed and replaced with new bone. The process keeps the skeleton strong and helps it to maintain a balance of minerals. In the course of osteonecrosis, however, the healing process is usually ineffective and the bone tissues break down faster than the body can repair them. If left untreated, the disease progresses, the bone collapses
The following disorders may be associated with the development of Osteonecrosis.
Vasculitis is a common disorder characterized by an inflammation of the blood vessel walls. This inflammation causes a narrowing of the inside of the vessel and can obstruct the flow of blood to the tissues (ischemia). The lack of blood may cause damage to the tissues (necrosis), possible formation of blood clots (thrombosis), or a weakening or ballooning which can possibly cause a rupture of the vessel wall (aneurysm). Osteonecrosis can occur in people with vasculitis when blood flow has been obstructed to the bone or joint. (For more information on this disorder, choose “Vasculitis” as your search term in the Rare Disease Database.)
Rheumatoid Arthritis is an inflammatory autoimmune disease in which the body’s natural defenses against foreign agents (antibodies & lymphocytes) attack healthy joints. This disorder is characterized by a lack of appetite (anorexia), fatigue, painful and deformed joints, early morning stiffness chiefly in the hands, knees, feet, jaw, and spine. People with Arthritis are at increased risk of also developing Osteonecrosis. (For more information on this disorder, choose “Arthritis” as your search term in the Rare Disease Database.)
Lupus (also known as SLE or Systemic Lupus Erythematosus) is an inflammatory connective tissue disease that can affect many parts of the body including the joints, skin and internal organs. Lupus is a disease of the body’s immune system, most often striking young women between the ages of 15 and 35 years. People who have Lupus are also at increased risk of developing Osteonecrosis. (For more information on this disorder, choose “Lupus” as your search term in the Rare Disease Database.)
Legg-Calve-Perthes Syndrome is a rare disease affecting the hip joint.LCPD usually occurs in children aged 4-10 years. Abnormalities in bone growth early in life may result in permanent deformity of the hip joint several years later. Osteonecrosis of the femoral head is often seen in those people with Legg-Calve-Perthes Disease. (For more information on his disorder, choose “Legg-Calve-Perthes” as your search term in the Rare Disease Database.)
Gaucher’s Disease is an inherited disease of lipid metabolism caused by the failure to produce the enzyme glucocerebrosidase. It is the most common of the 14 known lipid storage disorders which includes Tay-Sachs, Fabry’s Disease, and Niemann-Pick Disease. There are three types of Gaucher’s Disease Type I, II and III. All three are characterized by the presence of Gaucher (lipid-laden) cells in the bone marrow and other organs such as the spleen and liver. Bone deterioration (Osteonecrosis) is a major symptom of this disease and can affect any part of the body. (For more information on this disorder, choose “Gaucher” as your search term in the Rare Disease Database.)
Sickle Cell Disease is an inherited blood disease. Symptomatic of this disease are the “crisis periods” which often occur in conjunction with other infections. It is characterized by joint pain (arthralgia), fever, severe abdominal pain, vomiting, and damage to the head of the femur bone (osteonecrosis). (For more information on this disorder, choose “Sickle Cell” as your search term in the Rare Disease Database.)
Polycythemia Vera is a chronic proliferative disorder of the bone marrow. It is characterized by an increase in the number of red blood cells (erythrocytosis) and hemoglobin concentration in the blood. Osteonecrosis can occur in Polycythemia Vera. (For more information on this disorder, choose “Polycythemia Vera” as your search term in the Rare Disease Database.)
Caisson Disease, also called “Decompression Sickness” or the “Bends”, is a disorder caused by the formation of nitrogen bubbles in the tissues and blood. This occurs from a very rapid reduction of air pressure after rising quickly from deep water with high atmospheric pressure, to normal air pressure. It is characterized by painful joints, bone deterioration (Osteonecrosis), chest tightness, giddiness, abdominal pain, vomiting and visual difficulties. In some with this disorder there may also be convulsions and paralysis.
Since being diagnosed I have started a group on facebook,which I have many people from around the world in it. I cannot stress enough how painful, debilitating this disease is.
Every year 20,000 in USA diagnosed and over 50,000 a year worldwide diagnosed.
Some famous people that also have osteonecrosis are
Mike Napoli Famous Baseball player, Bo Jackson Famous football player , Singer Eddie Van Halen , Brett Favre Famous Football Player,John Montefusco Famous baseball player,Rudy Galindo famous skater. Steve Perry, Famous singer of Journey
Avascular Necrosis Lets spread The word to get more and better research